The CAPZA2 Polyclonal Antibody (CAB2054) is a valuable tool for researchers studying CAPZA2, a protein involved in actin filament capping and regulation of cell morphology. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CAPZA2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and cancer research.
CAPZA2 is known for its role in stabilizing actin filaments and controlling cell shape, making it a crucial player in processes like cell migration and division. Dysregulation of CAPZA2 has been implicated in cancer progression and metastasis, highlighting its importance as a potential therapeutic target. By studying the function of CAPZA2, researchers can gain insights into how it influences cellular processes and potentially develop novel strategies for cancer treatment and other related conditions.
Product Name:
CAPZA2 Rabbit Polyclonal Antibody
SKU:
CAB2054
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA2 (NP_006127.1).
actin cytoskeleton, cortical cytoskeleton, cytosol, extracellular exosome, extracellular region
Calculated MW:
33kDa
Observed MW:
38kDa
The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end.
Purification Method:
Affinity purification
Gene ID:
830
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CAPZA2 Rabbit pAb (CAB2054) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
