The CAPS Antibody (PAC060973) is a highly specific polyclonal antibody designed for research involving the CAPS protein, a key player in the process of inflammatory immune responses. Raised in rabbits, this antibody exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By binding to the CAPS protein, researchers can detect and analyze its expression in different cell types, making it a valuable tool for studies in immunology and cancer research.
CAPS, also known as Calcineurin B-like Protein 1, is a crucial regulator of immune responses, playing a critical role in the activation of inflammatory pathways. Dysregulation of CAPS has been implicated in various diseases, including autoimmune disorders and chronic inflammatory conditions. Investigating the function of CAPS is essential for understanding the underlying mechanisms of these diseases and ultimately developing targeted therapies to modulate immune responses effectively.
IHC image of PACO60973 diluted at 1:200 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Calcium-binding protein. May play a role in cellular signaling events (Potential).
Synonyms:
Calcyphosin (Calcyphosine), CAPS
UniProt Protein Function:
CAPS: Calcium-binding protein. May play a role in cellular signaling events (Potential).
UniProt Protein Details:
Protein type:Calcium-binding
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cytoplasm; vesicle
Molecular Function:calcium ion binding
NCBI Summary:
This gene encodes a calcium-binding protein, which may play a role in the regulation of ion transport. A similar protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as R2D5 antigen in rabbit. Alternative splicing of this gene generates two transcript variants. [provided by RefSeq, Jul 2008]
