CAPN9 Rabbit Polyclonal Antibody (CAB17085)
- SKU:
- CAB17085
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | CAPN9 Rabbit Polyclonal Antibody |
SKU: | CAB17085 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 391-690 of human CAPN9 (NP_006606.1). |
Sequence: | QEEC SFLV ALMQ KDRR KLKR FGAN VLTI GYAI YECP DKDE HLNK DFFR YHAS RARS KTFI NLRE VSDR FKLP PGEY ILIP STFE PHQE ADFC LRIF SEKK AITR DMDG NVDI DLPE PPKP TPPD QETE EEQR FRAL FEQV AGED MEVT AEEL EYVL NAVL QKKK DIKF KKLS LISC KNII SLMD TSGN GKLE FDEF KVFW DKLK QWIN LFLR FDAD KSGT MSTY ELRT ALKA AGFQ LSSH LLQL IVLR YADE ELQL DFDD FLNC LVRL ENAS RVFQ ALST KNKE FIHL NINE FIHL TMNI |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | GC36; nCL-4; CAPN9 |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm |
Calculated MW: | 79kDa |
Observed MW: | Refer to figures |
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10753 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |