CAPN7 Rabbit Polyclonal Antibody (CAB17666)
- SKU:
- CAB17666
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CAPN7 Rabbit Polyclonal Antibody |
SKU: | CAB17666 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human CAPN7 (NP_055111.1). |
Sequence: | RDHE GRYS EAVF YYKE AAQA LIYA EMAG SSLE NIQE KITE YLER VQAL HSAV QSKS ADPL KSKH QLDL ERAH FLVT QAFD EDEK ENVE DAIE LYTE AVDL CLKT SYET ADKV LQNK LKQL ARQA LDRA EALS EPLT KPVG KISS TSVK PKPP PVRA HFPL GANP FLER PQSF ISPQ SCDA QGQR YTAE EIEV LRTT SKIN G |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | PALBH; CALPAIN7; CAPN7 |
Positive Sample: | Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | centrosome, cytosol, extracellular exosome, nucleus |
Calculated MW: | 93kDa |
Observed MW: | 93kDa |
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity.
Purification Method: | Affinity purification |
Gene ID: | 23473 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |