The Capn14 Polyclonal Antibody (PAC051386) is a valuable tool for researchers studying Capn14, an important protein involved in various cellular processes. Raised in rabbits, this antibody exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the Capn14 protein, this antibody enables detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and signal transduction pathways.Capn14, also known as calpain 14, is a member of the calpain family of intracellular proteases that play key roles in cell signaling, cytoskeletal remodeling, and apoptosis.
Dysregulation of calpains has been implicated in various diseases, including muscular dystrophy, neurodegenerative disorders, and cancer. Therefore, understanding the function and regulation of Capn14 is essential for unraveling its contribution to these pathological conditions and potential therapeutic interventions.By utilizing the Capn14 Polyclonal Antibody, researchers can gain valuable insights into the role of Capn14 in cellular processes and disease pathogenesis. Its versatility and reliability make it a valuable tool for investigating the complex functions of Capn14 and its potential as a therapeutic target in various disease contexts.
Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN14 belongs to the calpain large subunit family.[supplied by OMIM, Mar 2008]
