CAPN11 Antibody (PACO22217)
- SKU:
- PACO22217
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CAPN11 Antibody (PACO22217) |
Antibody SKU: | PACO22217 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human CAPN11. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from HepG2 cells, Jurkat cells and HuvEc cells, using CAPN11 antibody. |
Background: | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. |
Synonyms: | Calpain-11; Calcium-activated neutral proteinase 11; CANP 11; |
UniProt Protein Function: | CAPN11: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Belongs to the peptidase C2 family.Protein type: EC 3.4.22.-; ProteaseChromosomal Location of Human Ortholog: 6p12Cellular Component: acrosomeMolecular Function: calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; peptidase activityBiological Process: proteolysis |
UniProt Protein Details: | |
NCBI Summary: | Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008] |
UniProt Code: | Q9UMQ6 |
NCBI GenInfo Identifier: | 218511961 |
NCBI Gene ID: | 11131 |
NCBI Accession: | Q9UMQ6.2 |
UniProt Secondary Accession: | Q9UMQ6,Q5T3G1, Q8N4R5, B2RA64 |
UniProt Related Accession: | Q9UMQ6 |
Molecular Weight: | 84,423 Da |
NCBI Full Name: | Calpain-11 |
NCBI Synonym Full Names: | calpain 11 |
NCBI Official Symbol: | CAPN11Â Â |
NCBI Official Synonym Symbols: | calpain11Â Â |
NCBI Protein Information: | calpain-11 |
UniProt Protein Name: | Calpain-11 |
UniProt Synonym Protein Names: | Calcium-activated neutral proteinase 11; CANP 11 |
Protein Family: | Calpain |
UniProt Gene Name: | CAPN11Â Â |
UniProt Entry Name: | CAN11_HUMAN |