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CAPG Monoclonal Antibody [PAT1D10AT] (CPAB0654)

SKU:
CPAB0654
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT1D10AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

CAPG Monoclonal Antibody [PAT1D10AT] (CPAB0654)

The CAPG Polyclonal Antibody (CPAB0654) is a powerful tool for researchers studying the cellular protein CAPG, which plays a role in various cellular processes including cytoskeletal remodeling and cell migration. This rabbit-raised antibody is highly specific and reactive with human samples, making it a reliable choice for Western blot applications. By binding to the CAPG protein, this antibody enables accurate detection and analysis of CAPG in a variety of cell types.CAPG, also known as gelsolin-like capping protein, is involved in actin filament capping and has been implicated in cancer metastasis and tumor progression.

Research into the function of CAPG is important for understanding its role in these processes, as well as its potential as a therapeutic target for cancer treatment. By studying the activity of CAPG, researchers can gain insights into how this protein influences cell behavior and potentially identify new strategies for combating cancer.

Product Name:CAPG Antibody
Product Sku:CPAB0654
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CAPG mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CAPG amino acids 1-348 purified from Ecoli.
Clone:PAT1D10AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:CAPG antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:CAPG is part of the gelsolin/villin family of actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated method, though it does not separate preformed actin filaments. By capping the barbed ends of actin filaments, CAPG contributes to the control of actin-based motility in non-muscle cells. CAPG is involved in macrophage function. CAPG is involved in regulating cytoplasmic and/or nuclear structures via possible interactions with actin. CAPG binds DNA. CAPG lacks a nuclear export sequence present in structurally related proteins. CAPG is a tumor suppressor protein that plays a role in the tumorigenic progression of certain cancers. Dysregulated expression of CAPG was found in premalignant and malignant oral carcinogenesis.
Synonyms:AFCP, CAPG, Macrophage-capping protein, Actin regulatory protein CAP-G, MCP.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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