The CANX Polyclonal Antibody (CAB6341) offered by Assay Genie is a valuable tool for researchers studying CANX, a multifunctional protein involved in protein folding and quality control in the endoplasmic reticulum. This antibody, generated in rabbits, boasts high reactivity with human samples and is suitable for use in Western blot applications. By binding to the CANX protein, researchers can effectively detect and analyze its presence in a variety of cell types, making it an essential tool for investigations in cell biology and protein science.
CANX, also known as calnexin, plays a crucial role in ensuring proper protein folding and glycosylation, thereby contributing to cellular homeostasis and function. Dysregulation of CANX has been linked to a range of diseases, including neurodegenerative disorders and cancer, underscoring its importance in cellular health. By studying CANX with the help of this antibody, researchers can gain insight into its function and potential therapeutic targets for various diseases.
Product Name:
CANT1 Rabbit Polyclonal Antibody
SKU:
CAB6341
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 62-231 of human CANT1 (NP_620148.1).
Endoplasmic reticulum membrane, Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein.
Calculated MW:
45kDa
Observed MW:
45kDa
This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
124583
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using (CAB6341) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
