CAMKK2 Rabbit Polyclonal Antibody (CAB9899)
- SKU:
- CAB9899
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | CAMKK2 Rabbit Polyclonal Antibody |
SKU: | CAB9899 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CAMKK2 (NP_006540.3). |
Sequence: | MSSC VSSQ PSSN RAAP QDEL GGRG SSSS ESQK PCEA LRGL SSLS IHLG MESF IVVT ECEP GCAV DLGL ARDR PLEA DGQE VPLD TSGS QARP HLSG RKLS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | CAMKK; CAMKKB; CAMKK2 |
Positive Sample: | HeLa,SH-SY5Y,LNCaP |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Nucleus. |
Calculated MW: | 65kDa |
Observed MW: | 68kDa/70kDa |
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.
Purification Method: | Affinity purification |
Gene ID: | 10645 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |