The Calretinin Polyclonal Antibody (CAB9807) is a vital tool for researchers studying calretinin, a calcium-binding protein involved in various cellular processes. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to the calretinin protein, researchers can accurately detect and analyze its expression in different cell types, making it ideal for investigations in neuroscience, developmental biology, and cancer research.
Calretinin is known for its role in neuronal development, synaptic plasticity, and tumor progression, making it a key target for understanding neurological disorders and cancer biology. By studying the function of calretinin, researchers can uncover insights into diseases such as Alzheimer's, epilepsy, and mesothelioma. The Calretinin Polyclonal Antibody provides a reliable tool for advancing research in these crucial areas of study.
Product Name:
CALB2 Rabbit Polyclonal Antibody
SKU:
CAB9807
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human Calretinin (NP_001731.2).
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
794
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Calretinin Rabbit pAb (CAB9807) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
