Calreticulin Polyclonal Antibody (CAB21665)
- SKU:
- CAB21665
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- IHC
Frequently bought together:
Description
Product Name: | Calreticulin Polyclonal Antibody |
SKU: | CAB21665 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-417 of human Calreticulineticulin (NP_004334.1). |
Sequence: | PAVY FKEQ FLDG DGWT SRWI ESKH KSDF GKFV LSSG KFYG DEEK DKGL QTSQ DARF YALS ASFE PFSN KGQT LVVQ FTVK HEQN IDCG GGYV KLFP NSLD QTDM HGDS EYNI MFGP DICG PGTK KVHV IFNY KGKN VLIN KDIR CKDD EFTH LYTL IVRP DNTY EVKI DNSQ VESG SLED DWDF LPPK KIKD PDAS KPED WDER AKID DPTD SKPE DWDK PEHI PDPD AKKP EDWD EEMD GEWE PPVI QNPE YKGE WKPR QIDN PDYK GTWI HPEI DNPE YSPD PSIY AYDN FGVL GLDL WQVK SGTI FDNF LITN DEAY AEEF GNET WGVT KAAE KQMK DKQD EEQR LKEE EEDK KRKE EEEA EDKE DDED KDED EEDE EDKE EDEE EDVP GQAK DEL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | RO; CRT; SSA; cC1qR; HEL-S-99n; Calreticulin |
Positive Sample: | HL-60,SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | Cell surface, Cytoplasm, Endoplasmic reticulum lumen, Sarcoplasmic reticulum lumen, Secreted, cytosol, extracellular matrix, extracellular space. |
Calculated MW: | 47kDa |
Observed MW: | 55kDa |
Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.
Purification Method: | Affinity purification |
Gene ID: | 811 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |