Calpain small subunit 1 Rabbit Monoclonal Antibody (CAB8859)
- SKU:
- CAB8859
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Calpain small subunit 1 Rabbit Monoclonal Antibody |
SKU: | CAB8859 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Calpain small subunit 1 (P04632). |
Sequence: | MFLV NSFL KGGG GGGG GGGG LGGG LGNV LGGL ISGA GGGG GGGG GGGG GGGG GGGG TAMR ILGG VISA ISEA AAQY NPEP PPPR THYS NIEA NESE EVRQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CANP; CDPS; CSS1; CANPS; CAPN4; CALPAIN4; Calpain small subunit 1 |
Positive Sample: | 293T,A-549,Mouse brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm. |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 826 |
Clone Number: | ARC1326 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |