The Calpain 2 Rabbit Monoclonal Antibody (CAB4066) is a valuable tool for researchers studying the protein calpain 2, an essential member of the calpain family of proteins involved in various cellular processes. This antibody, produced in rabbits, has high specificity and sensitivity for detecting calpain 2 in human samples, making it ideal for use in Western blot applications.Calpain 2 is known to play a critical role in cell signaling, protein turnover, and cytoskeletal dynamics, making it a key player in processes such as cell migration, differentiation, and apoptosis. Dysregulation of calpain 2 has been implicated in various diseases, including cancer, neurodegenerative disorders, and muscular dystrophies, making it a valuable target for research.
By using the Calpain 2 Rabbit Monoclonal Antibody (CAB4066), researchers can effectively study the expression and activity of calpain 2 in different cell types and tissue samples, providing valuable insights into its functions and potential therapeutic implications. With its high specificity and sensitivity, this antibody is a reliable tool for advancing research in cell biology, molecular biology, and disease mechanisms related to calpain 2.
Product Name:
Calpain 2 Rabbit Monoclonal Antibody
SKU:
CAB4066
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human Calpain 2 (P17655).
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
824
Clone Number:
ARC0891
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Calpain 2 Rabbit mAb (CAB4066) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
