The Calpain-2 Polyclonal Antibody is a vital tool for researchers studying calpain-2, a calcium-dependent protease involved in numerous cellular processes. This antibody, generated from rabbit immunizations, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for Western blotting applications.Calpain-2 is known for its role in cell signaling, cytoskeletal remodeling, and apoptosis, making it a key player in various physiological and pathological conditions. By targeting the calpain-2 protein, this antibody allows for the detection and analysis of calpain-2 levels in different cell types, offering valuable insights into its function and potential therapeutic applications.
With its ability to aid in the investigation of calpain-2's involvement in processes such as cell migration, differentiation, and disease development, the Calpain-2 Polyclonal Antibody is an essential tool for researchers in the fields of cell biology, biochemistry, and molecular biology. Its versatility and reliability make it a valuable asset for studies aiming to elucidate the complex mechanisms regulated by calpain-2.
Product Name:
Calpain 2 Polyclonal Antibody
SKU:
CAB2671
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 520-700 of human Calpain 2 (NP_001739.2).
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
824
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Calpain 2 Rabbit pAb (CAB2671).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
