The Calmodulin 1-2-3 Rabbit Monoclonal Antibody (CAB4885) is a powerful tool for researchers studying calmodulin, a critical protein involved in calcium signaling and cellular regulation. This antibody, raised in rabbits, is highly specific for calmodulin isoforms 1, 2, and 3 in humans, and has been validated for use in various applications, including immunofluorescence, immunohistochemistry, and flow cytometry.Calmodulin is a ubiquitous calcium-binding protein that plays a key role in numerous cellular processes, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calmodulin function has been implicated in a variety of diseases, such as cardiovascular disorders, neurodegenerative diseases, and cancer.
By targeting calmodulin isoforms 1, 2, and 3, this antibody allows researchers to investigate the specific functions and localization of these important proteins in different cell types and tissues.With its high sensitivity and specificity, the Calmodulin 1-2-3 Rabbit Monoclonal Antibody (CAB4885) is an essential tool for advancing our understanding of calmodulin biology and its implications for human health. Researchers in the fields of molecular biology, biochemistry, and cell biology will benefit from using this antibody to elucidate the complex roles of calmodulin isoforms in both normal physiology and disease states.
Product Name:
Calmodulin 1/2/3 Rabbit Monoclonal Antibody
SKU:
CAB4885
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-149 of human Calmodulin (NP_008819.1).
This gene encodes a member of the EF-hand calcium-binding protein family. It is one of three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Purification Method:
Affinity purification
Gene ID:
801/805/808
Clone Number:
ARC0316
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Calmodulin 1/2/3 Rabbit mAb (CAB4885) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
