The CALM3 Polyclonal Antibody (CAB1161) is a valuable tool for researchers studying CALM3, a calcium-binding protein involved in various cellular processes, including intracellular signaling and ion transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CALM3 protein, this antibody enables the detection and analysis of CALM3 in different cell types, making it suitable for research in cell biology and neuroscience.
CALM3, also known as Calmodulin 3, plays a crucial role in mediating calcium-dependent signaling pathways, which are essential for processes such as muscle contraction, neurotransmitter release, and gene expression. Dysregulation of CALM3 function has been implicated in various diseases, including cardiovascular disorders and neurodegenerative conditions. By investigating the role of CALM3 in these pathological processes, researchers can gain valuable insights for the development of potential therapies targeting CALM3 signaling pathways.
Product Name:
CALM3 Rabbit Polyclonal Antibody
SKU:
CAB1161
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-149 of human CALM3 (NP_001734.1).
Sequence:
MADQ LTEE QIAE FKEA FSLF DKDG DGTI TTKE LGTV MRSL GQNP TEAE LQDM INEV DADG NGTI DFPE FLTM MARK MKDT DSEE EIRE AFRV FDKD GNGY ISAA ELRH VMTN LGEK LTDE EVDE MIRE ADID GDGQ VNYE EFVQ MMTA K
This gene encodes a member of a family of proteins that binds calcium and functions as a enzymatic co-factor. Activity of this protein is important in the regulation of the cell cycle and cytokinesis. Multiple alternatively spliced transcript variants have been observed at this gene.
Purification Method:
Affinity purification
Gene ID:
808
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse brain, using CALM3 antibody (CAB1161).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.