The CALHM1 Polyclonal Antibody (CAB7858) is a powerful tool for researchers studying CALHM1, a calcium homeostasis modulator 1 protein involved in various cellular functions, including calcium ion transport. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to CALHM1, this antibody enables precise detection and analysis of the protein in a range of cell types, making it an ideal choice for studies in neuroscience and molecular biology.
CALHM1 is known for its role in regulating calcium homeostasis in neurons and its involvement in cell signaling pathways related to synaptic transmission. Its functions have been implicated in neurological disorders such as Alzheimer's disease, making it a promising target for research in neurodegenerative diseases. By understanding the mechanisms by which CALHM1 influences calcium signaling, researchers can uncover new insights into disease pathogenesis and potentially develop novel therapeutic strategies for treating these conditions.
Product Name:
CALHM1 Rabbit Polyclonal Antibody
SKU:
CAB7858
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 202-346 of human CALHM1 (NP_001001412.3).
This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.
Purification Method:
Affinity purification
Gene ID:
255022
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CALHM1 Rabbit pAb (CAB7858) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
