The Calcoco2 Polyclonal Antibody (CAB7358) is a versatile tool for researchers studying the Calcoco2 protein, which plays a crucial role in various cellular processes, including autophagy and protein degradation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Calcoco2 protein, this antibody enables precise detection and analysis in a wide range of cell types, making it ideal for studies in cell biology and cancer research.Calcoco2, also known as Calcium binding and coiled-coil domain 2, is involved in the regulation of autophagy, a process that maintains cellular homeostasis by degrading and recycling damaged organelles and proteins.
Dysregulation of autophagy has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic conditions. Therefore, unraveling the function of Calcoco2 is essential for understanding the mechanisms underlying these diseases and developing targeted therapies.In conclusion, the Calcoco2 Polyclonal Antibody (CAB7358) is a valuable tool for researchers aiming to investigate the role of Calcoco2 in cellular processes and disease states. With its high specificity and reliability in Western blot applications, this antibody is a crucial asset for advancing research in the fields of cell biology, cancer biology, and autophagy.
Product Name:
CALCOCO2 Rabbit Polyclonal Antibody
SKU:
CAB7358
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human NDP52 (NP_005822.1).
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10241
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse pancreas, using NDP52 antibody (CAB7358) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
