RCAN1 Rabbit Polyclonal Antibody (CAB5326)
- SKU:
- CAB5326
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RCAN1 Rabbit Polyclonal Antibody |
SKU: | CAB5326 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-245 of human RCAN1 (NP_004405.3). |
Sequence: | DLQD LPSA TIAC HLDP RVFV DGLC RAKF ESLF RTYD KDIT FQYF KSFK RVRI NFSN PFSA ADAR LQLH KTEF LGKE MKLY FAQT LHIG SSHL APPN PDKQ FLIS PPAS PPVG WKQV EDAT PVIN YDLL YAIS KLGP GEKY ELHA ATDT TPSV VVHV CESD QEKE EEEE MERM RRPK PKII QTRR PE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78; RCAN1 |
Positive Sample: | SW480,SKOV3,U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, nucleus |
Calculated MW: | 28kDa |
Observed MW: | 31kDa |
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1827 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |