Calcineurin A Rabbit Monoclonal Antibody (CAB4346)
The Calcineurin A Rabbit Monoclonal Antibody (CAB4346) is a valuable tool for researchers investigating Calcineurin A, a key phosphatase enzyme involved in immune response regulation and cell signaling pathways. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity for detecting Calcineurin A in human samples, making it an ideal choice for various research applications.Calcineurin A plays a crucial role in T-cell activation and differentiation, making it a promising target for studying immune-related diseases such as autoimmune disorders, infections, and inflammatory conditions.
By targeting Calcineurin A, researchers can gain insight into the molecular mechanisms underlying immune response regulation and potentially identify new therapeutic strategies for manipulating immune function.With its superior performance in Western blot applications, the Calcineurin A Rabbit Monoclonal Antibody (CAB4346) offers researchers a reliable tool for investigating the function and regulation of Calcineurin A in various cell types and experimental settings. Its specificity and sensitivity make it a valuable asset for studies in immunology, cancer research, and beyond.
Product Name:
Calcineurin A Rabbit Monoclonal Antibody
SKU:
CAB4346
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 422-521 of human Calcineurin A (Q08209).
Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia.
Purification Method:
Affinity purification
Gene ID:
5530
Clone Number:
ARC0970
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Calcineurin A Rabbit mAb (CAB4346) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
