Calcineurin A Rabbit Monoclonal Antibody (CAB4346)
- SKU:
- CAB4346
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Calcineurin A Rabbit Monoclonal Antibody |
SKU: | CAB4346 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 422-521 of human Calcineurin A (Q08209). |
Sequence: | TLKG LTPT GMLP SGVL SGGK QTLQ SATV EAIE ADEA IKGF SPQH KITS FEEA KGLD RINE RMPP RRDA MPSD ANLN SINK ALTS ETNG TDSN GSNS SNIQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CALN; CCN1; CNA1; CALNA; DEE91; IECEE; PPP2B; ACCIID; CALNA1; IECEE1; Calcineurin A |
Positive Sample: | MCF7,U-937,C6,SH-SY5Y,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Nucleus, sarcolemma. |
Calculated MW: | 59kDa |
Observed MW: | 59kDa |
Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia.
Purification Method: | Affinity purification |
Gene ID: | 5530 |
Clone Number: | ARC0970 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |