The Calca Polyclonal Antibody (CAB16786) is a valuable tool for researchers studying the Calca protein, which plays a crucial role in various biological processes, including immune regulation and inflammation. This rabbit polyclonal antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications.Calca, also known as calcitonin gene-related peptide (CGRP), is a neuropeptide that acts as a vasodilator and is involved in pain signaling and neurogenic inflammation. It is implicated in a range of conditions, including migraine, inflammation, and neurologic disorders.
The Calca Polyclonal Antibody binds specifically to the Calca protein, enabling accurate detection and analysis in various cell types.By understanding the function and regulation of Calca, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets. The Calca Polyclonal Antibody is a valuable tool for advancing research in areas such as neurobiology, pain management, and inflammatory diseases.
Product Name:
CALCA Rabbit Polyclonal Antibody
SKU:
CAB16786
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-128 of CALCA (NP_001029125.1).
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
796
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using CALCA Rabbit pAb (CAB16786) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
