Calbindin Rabbit Polyclonal Antibody (CAB15035)
- SKU:
- CAB15035
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Calbindin Rabbit Polyclonal Antibody |
SKU: | CAB15035 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human Calbindin (NP_004920.1). |
Sequence: | MAES HLQS SLIT ASQF FEIW LHFD ADGS GYLE GKEL QNLI QELQ QARK KAGL ELSP EMKT FVDQ YGQR DDGK IGIV ELAH VLPT EENF LLLF RCQQ LKSC EEFM KTWR KYDT DHSG FIET EELK NFLK DLLE KANK TVDD TKLA EYTD LMLK LFDS NNDG KLEL TEMA RLLP VQEN FLLK FQGI KMCG KEFN KAFE LYDQ DGNG YIDE NELD ALLK DLCE KNKQ DLDI NNIT TYKK NIMA LSDG GKLY RTDL ALIL CAGD N |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | CALB; D-28K; Calbindin |
Positive Sample: | Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | axon, calyx of Held, cytosol, dendrite, dendritic spine, extracellular exosome, GABA-ergic synapse, glutamatergic synapse, hippocampal mossy fiber to CA3 synapse, neuron projection, nucleus, postsynaptic cytosol, presynaptic cytosol, synapse, terminal bouton |
Calculated MW: | 30kDa |
Observed MW: | 30kDa |
The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease.
Purification Method: | Affinity purification |
Gene ID: | 793 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |