The CADPS2 Polyclonal Antibody (CAB13821) is a valuable tool for researchers studying CADPS2, a calcium-dependent activator protein for secretion 2 involved in synaptic vesicle exocytosis. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blotting applications. By binding to the CADPS2 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in neuroscience and neurodegenerative disorders.
CADPS2 plays a crucial role in regulating synaptic transmission and neurotransmitter release, making it a key player in neuronal communication and brain function. Dysregulation of CADPS2 has been implicated in conditions such as Alzheimer's disease and schizophrenia, highlighting its importance in understanding brain disorders. By studying CADPS2, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for treatment.
Product Name:
CADPS2 Rabbit Polyclonal Antibody
SKU:
CAB13821
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human CADPS2 (NP_001009571.2).
This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
93664
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CADPS2 Rabbit pAb (CAB13821) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
