The CADPS Polyclonal Antibody (CAB17026) is a high-quality antibody designed for researchers studying CADPS, a synaptic vesicle protein involved in regulating neurotransmitter release. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By targeting the CADPS protein, this antibody enables accurate detection and analysis in a variety of cell types, making it well-suited for research in neurobiology and synaptic transmission.CADPS, also known as calcium-dependent activator protein for secretion, plays a crucial role in synaptic vesicle exocytosis and neurotransmitter release, making it a key player in neuronal communication.
Understanding the function of CADPS is essential for unraveling the mechanisms underlying synaptic transmission and neuronal signaling, providing valuable insights into neurological disorders such as Alzheimer's disease and Parkinson's disease. The CADPS Polyclonal Antibody offers researchers a powerful tool for investigating the role of CADPS in neuronal function and dysfunction.
Product Name:
CADPS Rabbit Polyclonal Antibody
SKU:
CAB17026
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1020-1100 of human CADPS (NP_899630.1).
Sequence:
MASD MIES CVKR TRIA FEVK LQKT SRST DFRV PQSI CTMF NVMV DAKA QSTK LCSM EMGQ EHQY HSKI DELI EETV KEMI T
This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.
Purification Method:
Affinity purification
Gene ID:
8618
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human breast cancer using CADPS Rabbit pAb (CAB17026) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
