The CADPS Polyclonal Antibody (CAB13186) is a versatile tool for researchers studying CADPS, a key protein involved in regulating synaptic vesicle exocytosis and neurotransmitter release. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications.CADPS, also known as calcium-dependent activator protein for secretion, plays a crucial role in the release of neurotransmitters in the brain, making it an important target for studies on synaptic transmission and neuronal communication.
The CADPS Polyclonal Antibody binds specifically to the CADPS protein, enabling precise detection and analysis in various cell types.Research on CADPS is essential for understanding the mechanisms underlying neurotransmitter release and synaptic plasticity, with implications for neurological disorders such as epilepsy, Alzheimer's disease, and Parkinson's disease. By studying CADPS and its functions, researchers can gain valuable insights into the pathophysiology of these conditions and potentially identify new therapeutic targets.
Product Name:
CADPS Rabbit Polyclonal Antibody
SKU:
CAB13186
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1020-1100 of human CADPS (NP_899630.1).
Sequence:
MASD MIES CVKR TRIA FEVK LQKT SRST DFRV PQSI CTMF NVMV DAKA QSTK LCSM EMGQ EHQY HSKI DELI EETV KEMI T
This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.
Purification Method:
Affinity purification
Gene ID:
8618
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CADPS Rabbit pAb (CAB13186) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
