The CADM3 Polyclonal Antibody (CAB4902) is a valuable tool for researchers studying CADM3, a cell adhesion molecule known for its role in cell-to-cell interactions and immune regulation. This antibody, produced in rabbits, specifically binds to CADM3 in human samples and is validated for use in Western blot applications.CADM3, also known as SynCAM3, is involved in synaptic adhesion and has been implicated in various physiological and pathological processes, including neuronal development, cancer metastasis, and immune responses. By targeting CADM3 with this polyclonal antibody, researchers can effectively study its expression, localization, and function in different cell types, providing insights into its role in immunology, neurobiology, and oncology.
Given CADM3's potential involvement in cancer progression, neurological disorders, and immune dysregulation, understanding its molecular mechanisms and regulatory functions is essential for developing targeted therapies and diagnostic tools. The CADM3 Polyclonal Antibody (CAB4902) enables precise detection and analysis of CADM3 protein, making it an invaluable asset for investigations in these fields.
Product Name:
CADM3 Rabbit Polyclonal Antibody
SKU:
CAB4902
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1).
Cell junction, Cell membrane, Single-pass type I membrane protein.
Calculated MW:
43kDa
Observed MW:
43kDa
The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene.
Purification Method:
Affinity purification
Gene ID:
57863
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CADM3 antibody (CAB4902) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
