The CADM2 Polyclonal Antibody (CAB11724) is a valuable tool for researchers studying CADM2, a cell adhesion molecule involved in synaptic connectivity and neurite outgrowth. This antibody is produced in rabbits and demonstrates high reactivity with human samples, making it ideal for Western blot applications. By specifically binding to CADM2, this antibody enables researchers to detect and analyze CADM2 expression in various cell types, facilitating studies in neuroscience and developmental biology.CADM2, also known as TSLC1, plays a crucial role in synaptic organization and neuronal development, making it a key factor in processes such as learning and memory.
Dysregulation of CADM2 has been implicated in neurological disorders such as autism, schizophrenia, and epilepsy. Research into the function of CADM2 is essential for understanding the molecular mechanisms underlying these conditions and may lead to the development of targeted therapies.Overall, the CADM2 Polyclonal Antibody (CAB11724) is a valuable tool for researchers investigating the role of CADM2 in synaptic connectivity and neurological disorders. Its high reactivity and specificity make it a reliable choice for studies aiming to uncover the intricate mechanisms governing brain development and function.
Product Name:
CADM2 Rabbit Polyclonal Antibody
SKU:
CAB11724
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-335 of human CADM2 (NP_001161147.1).
Cell junction, Cell membrane, Cell projection, Single-pass type I membrane protein, axon, synapse.
Calculated MW:
48kDa
Observed MW:
48kDa
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
253559
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse liver, using CADM2 Rabbit pAb (CAB11724) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
