Cadherin 16 Rabbit Polyclonal Antibody (CAB7882)
- SKU:
- CAB7882
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Cadherin 16 Rabbit Polyclonal Antibody |
SKU: | CAB7882 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-230 of human Cadherin 16 (NP_004053.1). |
Sequence: | KAQP AELS VEVP ENYG GNFP LYLT KLPL PREG AEGQ IVLS GDSG KATE GPFA MDPD SGFL LVTR ALDR EEQA EYQL QVTL EMQD GHVL WGPQ PVLV HVKD ENDQ VPHF SQAI YRAR LSRG TRPG IPFL FLEA SDRD EPGT ANSD LRFH ILSQ APAQ PSPD MFQL EPRL GALA LSPK GSTS LDHA LERT YQLL VQVK DMGD QASG HQAT ATVE |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | CDH16; Cadherin 16 |
Positive Sample: | A-549,293T,HepG2,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 90kDa |
Observed MW: | 110kDa |
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 1014 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |