The CACNG2 Polyclonal Antibody (CAB6537) is a valuable tool for researchers studying CACNG2, a protein involved in calcium signaling and neuronal function. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting CACNG2 in human samples, making it ideal for Western blot applications.CACNG2, also known as the Voltage-dependent calcium channel gamma-2 subunit, plays a crucial role in regulating calcium influx and synaptic transmission in neurons.
Dysregulation of CACNG2 has been implicated in various neurological disorders, including epilepsy and schizophrenia, making it a promising target for therapeutic interventions.By utilizing the CACNG2 Polyclonal Antibody, researchers can gain insights into the expression and function of CACNG2 in different cell types and tissues, advancing our understanding of its role in neuronal signaling and its potential as a therapeutic target for neurological disorders.
Product Name:
CACNG2 Rabbit Polyclonal Antibody
SKU:
CAB6537
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 204-323 of human CACNG2 (NP_006069.1).
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. The AMPA subtype of ionotropic glutamate receptors are ligand gated ion channels that are typically activated by glutamate released from presynaptic neuron terminals and mediate fast neurotransmission in excitatory synapses. TARPs thus play an important role in synaptic plasticity, learning and memory. Mutations in this gene cause an autosomal dominant form of cognitive disability.
Purification Method:
Affinity purification
Gene ID:
10369
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CACNG2 Antibody (CAB6537) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
