The CACNG1 Polyclonal Antibody (CAB10014) is a valuable tool for researchers studying CACNG1, a protein known to be involved in calcium channel regulation and neuronal signaling. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds to the CACNG1 protein, facilitating its detection and analysis in various cell types, making it an excellent choice for studies in neuroscience and neurology research.CACNG1, also known as the calcium channel gamma-1 subunit, plays a crucial role in controlling the function of voltage-gated calcium channels, which are essential for various cellular processes including neurotransmitter release and neuronal excitability.
Dysregulation of CACNG1 has been linked to neurological disorders such as epilepsy, Parkinson's disease, and Alzheimer's disease, making it a promising target for therapeutic interventions aimed at modulating calcium channel activity.The CACNG1 Polyclonal Antibody is a reliable tool for researchers seeking to explore the function and regulation of CACNG1 in health and disease. By enabling the detection and analysis of CACNG1 expression in different experimental settings, this antibody can provide valuable insights into the role of CACNG1 in neuronal physiology and its potential implications for neurological conditions.
Product Name:
CACNG1 Rabbit Polyclonal Antibody
SKU:
CAB10014
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-110 of human CACNG1 (NP_000718.1).
Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs).
Purification Method:
Affinity purification
Gene ID:
786
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of C6 cells using CACNG1 Rabbit pAb (CAB10014) at dilution of 1:300 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
