The CACNB2 Polyclonal Antibody (CAB16037) is specifically designed for research involving CACNB2, a key subunit of voltage-gated calcium channels that plays a crucial role in calcium signaling pathways. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the CACNB2 protein, this antibody allows for the detection and analysis of CACNB2 expression in various cell types, making it an ideal tool for studies in neuroscience and cardiovascular research.
CACNB2 is known to play a critical role in regulating calcium influx and signaling in neurons and cardiac muscle cells. Dysregulation of CACNB2 has been implicated in various neurological and cardiovascular disorders, making it a valuable target for research in these areas. Understanding the function and expression of CACNB2 is essential for unraveling the mechanisms underlying these conditions and developing targeted therapies to address them.
Product Name:
CACNB2 Rabbit Polyclonal Antibody
SKU:
CAB16037
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 481-660 of human CACNB2 (NP_963890.2).
This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
783
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse heart, using CACNB2 Rabbit pAb (CAB16037) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
