CACNA2D1 Rabbit Polyclonal Antibody (CAB15260)
- SKU:
- CAB15260
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CACNA2D1 Rabbit Polyclonal Antibody |
SKU: | CAB15260 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human CACNA2D1 (NP_000713.2). |
Sequence: | DIKV EIRN KMID GESG EKTF RTLV KSQD ERYI DKGN RTYT WTPV NGTD YSLA LVLP TYSF YYIK AKLE ETIT QARS KKGK MKDS ETLK PDNF EESG YTFI APRD YCND LKIS DNNT EFLL NFNE FIDR KTPN NPSC NADL INRV LLDA GFTN ELVQ NYWS KQKN IKGV KARF VVTD GGIT RVYP KEAG ENWQ ENPE TYED SFYK RSLD NDNY VFTA PYFN KSGP GAYE SGIM VSKA VEIY IQGK LLKP AVV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | CACNA2; CCHL2A; DEE110; CACNL2A; LINC01112; lncRNA-N3; CACNA2D1 |
Positive Sample: | LO2,293T,Mouse brain,Mouse heart,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 125kDa |
Observed MW: | 124kDa/150kDa |
The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion.
Purification Method: | Affinity purification |
Gene ID: | 781 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |