The CACNA1S Polyclonal Antibody is a valuable tool for researchers studying the CACNA1S protein, which is involved in muscle contractions and plays a critical role in muscle function. This antibody, derived from rabbits, exhibits high reactivity with human samples and is specifically validated for Western blot applications.CACNA1S, also known as the alpha-1 subunit of the dihydropyridine-sensitive L-type calcium channel, is essential for transmitting electrical signals in muscle cells. Dysregulation of CACNA1S has been linked to various muscle disorders, making it a key target for investigating neuromuscular diseases and potential therapeutic interventions.
By targeting the CACNA1S protein, researchers can gain insights into the mechanisms of muscle contraction and explore potential pathways for treating muscle-related disorders. This antibody enables the detection and analysis of CACNA1S in a variety of cell types, making it an invaluable tool for studies in physiology, pharmacology, and muscle biology.
This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility.
Purification Method:
Affinity purification
Gene ID:
779
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of mouse skeletal muscle cells using CACNA1S Rabbit pAb (CAB23062) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
