The Cabyr Antibody (PACO08133) is a highly specific and reliable tool for studying the CD300A protein in various research applications. This polyclonal antibody is produced in rabbits and is optimized for detecting CD300A in human samples through Western blot analysis. CD300A is a key player in immune regulation, functioning to inhibit immune responses and modulate inflammation. Research areas such as immunology and cancer can greatly benefit from the use of this antibody to investigate the role of CD300A in disease processes.
By targeting CD300A, researchers can potentially uncover new insights into the development of therapies for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Unlock the potential of CD300A research with the Cabyr Antibody.
CABYR: May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium. 6 isoforms of the human protein are produced by alternative splicing.Protein type: Cancer Testis Antigen (CTA); Calcium-bindingChromosomal Location of Human Ortholog: 18q11.2Cellular Component: cytoskeleton; cytoplasm; nucleolus; nucleusMolecular Function: enzyme binding; protein heterodimerization activity; calcium ion binding; SH3 domain bindingBiological Process: sperm capacitation
UniProt Protein Details:
NCBI Summary:
To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2013]