The CABP2 Polyclonal Antibody (PACO05889) is a crucial tool for researchers studying CABP2, a protein involved in calcium signaling pathways. This antibody, produced in rabbits, exhibits high specificity for CABP2 in human samples and is validated for use in Western blot applications. By binding to CABP2, the antibody allows for precise detection and analysis in a variety of cell types, making it an essential tool for studies in neuroscience and cellular biology.CABP2, also known as caldendrin, plays a pivotal role in regulating intracellular calcium levels and synaptic transmission in the brain. Its involvement in these processes makes it a key player in neurological disorders such as epilepsy, Alzheimer's disease, and Parkinson's disease.
Research into the function of CABP2 is essential for developing therapies targeting these conditions and understanding the mechanisms underlying synaptic plasticity.In conclusion, the PACO05889 antibody is a valuable resource for scientists investigating the role of CABP2 in calcium signaling and synaptic transmission. Its high specificity and reliability in Western blot applications make it an indispensable tool for advancing our understanding of neurological disorders and developing targeted therapies to treat them.
Antibody Name:
CABP2 Antibody (PACO05889)
Antibody SKU:
PACO05889
Size:
50ug
Host Species:
Rabbit
Tested Applications:
WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic Peptide
Form:
Liquid
Storage Buffer:
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Purification Method:
Affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CABP2
UniProt Protein Function:
CABP2: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Calcium-bindingChromosomal Location of Human Ortholog: 11q13.1Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; plasma membraneMolecular Function: calcium ion bindingBiological Process: signal transductionDisease: Deafness, Autosomal Recessive 93
UniProt Protein Details:
NCBI Summary:
This gene belongs to a subfamily of calcium binding proteins that share similarity to calmodulin. Like calmodulin, these family members can likely stimulate calmodulin-dependent kinase II and the protein phosphatase calcineurin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
