CABLES1 Rabbit Polyclonal Antibody (CAB10335)
- SKU:
- CAB10335
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CABLES1 Rabbit Polyclonal Antibody |
SKU: | CAB10335 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CABLES1 (NP_612384.1). |
Sequence: | MLSK RGCH ARIY ADFP IRRL ISQR SSLE TLED IEEN APLR RCRT LSGS PRPK NFKK IHFI KNMR QHDT RNGR IVLI SGRR SFCS IFSV LPYR DSTQ VGDL KLDG GRQS TGAV SLKE IIGL EGVE LGAD GKTV SYTQ FLLP TNAF GARR NTID STSS FSQF RNLS HRSL SIGR ASGT QGSL DTGS DLGD FMDY DPNL LDDP QWPC GKHK RVLI FPSY MTTV IDYV KPSD LKKD MNET FKEK FPHI KLTL SKIR SLKR EMRK LAQE DCGL EEPT VAMA FVYF EKLA LKGK LNKQ NRKL CAGA CVLL AAKI GSDL KKHE VKHL IDKL EEKF RLNR RELI AFEF PVLV ALEF ALHL PEHE VMPH YRRL VQSS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | CABL1; IK3-1; CABLES; HsT2563; CABLES1 |
Positive Sample: | MCF7,HT-29,A-549,HL-60,HeLa,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 68kDa |
Observed MW: | 67kDa |
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 91768 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |