Carbonic Anhydrase 9 (CA9/G250) Rabbit Monoclonal Antibody (CAB4934)
- SKU:
- CAB4934
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | Carbonic Anhydrase 9 (CA9/G250) Rabbit Monoclonal Antibody |
SKU: | CAB4934 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Carbonic Anhydrase 9 (CA9/G250) (Q16790). |
Sequence: | HSVQ LTLP PGLE MALG PGRE YRAL QLHL HWGA AGRP GSEH TVEG HRFP AEIH VVHL STAF ARVD EALG RPGG LAVL AAFL EEGP EENS AYEQ LLSR LEEI A |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | MN; CAIX; Carbonic Anhydrase 9 (CA9/G250) |
Positive Sample: | HT-29,SW620 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Nucleus, Single-pass type I membrane protein, microvillus membrane, nucleolus. |
Calculated MW: | 50kDa |
Observed MW: | 35-58kDa |
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
Purification Method: | Affinity purification |
Gene ID: | 768 |
Clone Number: | ARC1275 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |