The CA6 Polyclonal Antibody (PACO22235) is a valuable tool for researchers studying the role of carbonic anhydrase 6 (CA6) in various biological processes. Carbonic anhydrase 6 is a zinc metalloenzyme that plays a crucial role in maintaining acid-base balance in the body, particularly in the kidneys and reproductive organs.This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to CA6 protein, this antibody allows for accurate detection and analysis of CA6 expression in different cell types, making it an ideal choice for studies in molecular biology, physiology, and pathology.
A better understanding of the function and regulation of CA6 is essential for the development of diagnostic tools and therapeutic interventions for conditions related to acid-base imbalance, such as renal tubular acidosis and infertility. The CA6 Polyclonal Antibody is a valuable resource for researchers aiming to uncover the role of CA6 in health and disease.
Antibody Name:
CA6 Antibody (PACO22235)
Antibody SKU:
PACO22235
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human CA6.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from LOVO cells and HepG2 cells, using CA6 antibody.
Background:
Reversible hydration of carbon dioxide. Its role in saliva is unknown.
CA6: Reversible hydration of carbon dioxide. Its role in saliva is unknown. Belongs to the alpha-carbonic anhydrase family.
UniProt Protein Details:
Protein type:Secreted, signal peptide; Lyase; Secreted; Energy Metabolism - nitrogen; EC 4.2.1.1
Chromosomal Location of Human Ortholog: 1p36.2
Cellular Component: extracellular region; extracellular space
Molecular Function:carbonate dehydratase activity
Biological Process: bicarbonate transport; detection of chemical stimulus involved in sensory perception of bitter taste
NCBI Summary:
The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008]
