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CA6 Antibody (PACO00490)

SKU:
PACO00490
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
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Description

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CA6 Antibody (PACO00490)

The CA6 Polyclonal Antibody (PACO00490) is a valuable tool for researchers studying the CA6 protein, which is involved in various cellular functions, including metabolism and cell signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the CA6 protein, this antibody allows for the detection and analysis of CA6 expression in different cell types, making it an excellent choice for studies in biochemistry and cancer research.

CA6, also known as carbonic anhydrase VI, is a key enzyme that plays a crucial role in maintaining acid-base balance in the body and facilitating various physiological processes. Understanding the function and regulation of CA6 is essential for uncovering its potential implications in diseases such as cancer, metabolic disorders, and kidney diseases. By investigating the role of CA6 in these conditions, researchers may identify novel therapeutic targets and treatment strategies that could benefit patients.

Antibody Name:CA6 Antibody
Antibody SKU:PACO00490
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:WB:1:500-1:2000
Species Reactivity:Human
Immunogen:synthesized peptide derived from the C-terminal region of human CA VI.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:CA6; Carbonic anhydrase 6; Carbonate dehydratase VI; Carbonic anhydrase VI; CA-VI; Salivary carbonic anhydrase; Secreted carbonic anhydrase
UniProt Protein Function:CA6: Reversible hydration of carbon dioxide. Its role in saliva is unknown. Belongs to the alpha-carbonic anhydrase family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Lyase; Secreted; Energy Metabolism - nitrogen; EC 4.2.1.1

Chromosomal Location of Human Ortholog: 1p36.2

Cellular Component: extracellular region; extracellular space

Molecular Function:carbonate dehydratase activity

Biological Process: bicarbonate transport; detection of chemical stimulus involved in sensory perception of bitter taste

NCBI Summary:The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008]
UniProt Code:P23280
NCBI GenInfo Identifier:116241278
NCBI Gene ID:765
NCBI Accession:P23280.3
UniProt Secondary Accession:P23280,Q5FBW3, Q5FC00, Q96QX8, Q9UF03, E7EMQ1,
UniProt Related Accession:P23280
Molecular Weight:28,687 Da
NCBI Full Name:Carbonic anhydrase 6
NCBI Synonym Full Names:carbonic anhydrase 6
NCBI Official Symbol:CA6  
NCBI Official Synonym Symbols:CA-VI; GUSTIN  
NCBI Protein Information:carbonic anhydrase 6
UniProt Protein Name:Carbonic anhydrase 6
UniProt Synonym Protein Names:Carbonate dehydratase VI; Carbonic anhydrase VI; CA-VI; Salivary carbonic anhydrase; Secreted carbonic anhydrase
Protein Family:Carbonic anhydrase
UniProt Gene Name:CA6  
UniProt Entry Name:CAH6_HUMAN

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