The CA3 Polyclonal Antibody (CAB13473) is a valuable tool for researchers studying the CA3 protein, which is known for its role in various biological processes such as calcium signaling and neurotransmission. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.CA3 is a key enzyme that plays a crucial role in the regulation of calcium levels in cells, making it essential for proper cell function. Dysregulation of CA3 has been implicated in various diseases such as Alzheimer's disease and epilepsy, highlighting the importance of studying this protein in the context of neurological disorders.
By using the CA3 Polyclonal Antibody, researchers can effectively detect and analyze the expression of the CA3 protein in different cell types, providing valuable insights into its function and potential implications in disease pathogenesis. This antibody is a valuable tool for studies in neuroscience, pharmacology, and drug development aiming to target CA3 for therapeutic interventions.
Product Name:
CA3 Rabbit Polyclonal Antibody
SKU:
CAB13473
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CA3 (NP_005172.1).
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.
Purification Method:
Affinity purification
Gene ID:
761
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse skeletal muscle, using CA3 antibody (CAB13473) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
