The CA2 Polyclonal Antibody (CAB1440) is specially designed for research involving the CA2 protein, an enzyme involved in regulating pH balance in cells. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it an excellent tool for studies in biochemistry and cell biology.The CA2 enzyme plays a crucial role in maintaining cellular pH homeostasis, with implications in various physiological processes such as bone resorption, calcification, and tumor progression. By targeting the CA2 protein, researchers can investigate its function and mechanism of action in different cell types, leading to a better understanding of its role in health and disease.
The versatility of the CA2 Polyclonal Antibody makes it suitable for a range of applications, including Western blotting, immunofluorescence, and immunohistochemistry. Its high sensitivity and specificity ensure reliable and reproducible results, making it an indispensable tool for researchers studying the role of CA2 in biological processes and disease pathogenesis.
The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
760
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Carbonic Anhydrase 2 (CA2) antibody (CAB1440) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
