The CA11 Polyclonal Antibody is specifically designed for research involving CA11, a cell surface molecule with a potential role in cancer development and progression. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to the CA11 protein, this antibody enables precise detection and analysis in various cell types, making it an excellent tool for oncology research.CA11, also referred to as a potential cancer-associated antigen, is believed to play a critical role in tumorigenesis and metastasis. Its potential involvement in cancer makes it a promising target for further investigation in cancer biology and therapeutic development.
Understanding the function and regulation of CA11 is essential for uncovering novel approaches to diagnosing and treating cancer effectively.In conclusion, the CA11 Polyclonal Antibody is a valuable tool for researchers studying the role of CA11 in cancer biology and exploring its potential as a target for therapeutic interventions. Its high reactivity and specificity make it a reliable choice for Western blot analysis, providing insights into the function of CA11 in various cellular contexts.
Antibody Name:
CA11 Antibody (PACO25436)
Antibody SKU:
PACO25436
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Carbonic anhydrase-related protein 11 protein (24-328AA)
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO25436 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human stomach tissue using PACO25436 at dilution of 1:100.
Background:
Does not have a catalytic activity.
Synonyms:
Carbonic anhydrase-related protein 11 (CA-RP XI) (CA-XI) (CARP XI) (Carbonic anhydrase-related protein 2) (CA-RP II) (CARP-2), CA11, CARP2
UniProt Protein Function:
Does not have a catalytic activity.
UniProt Protein Details:
NCBI Summary:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008]
