C8B Rabbit Polyclonal Antibody (CAB8324)
- SKU:
- CAB8324
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | C8B Rabbit Polyclonal Antibody |
SKU: | CAB8324 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 55-350 of human C8B (NP_000057.2). |
Sequence: | SVDV TLMP IDCE LSSW SSWT TCDP CQKK RYRY AYLL QPSQ FHGE PCNF SDKE VEDC VTNR PCRS QVRC EGFV CAQT GRCV NRRL LCNG DNDC GDQS DEAN CRRI YKKC QHEM DQYW GIGS LASG INLF TNSF EGPV LDHR YYAG GCSP HYIL NTRF RKPY NVES YTPQ TQGK YEFI LKEY ESYS DFER NVTE KMAS KSGF SFGF KIPG IFEL GISS QSDR GKHY IRRT KRFS HTKS VFLH ARSD LEVA HYKL KPRS LMLH YEFL QRVK RLPL EYSY GEYR DLFR DFGT HYIT EAVL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | C82; C8B |
Positive Sample: | HepG2,Jurkat,HeLa,THP-1,Raji,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 67kDa |
Observed MW: | 67kDa |
This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 732 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |