The C7 Polyclonal Antibody (CAB5394) is a powerful tool for researchers studying the protein C7. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the C7 protein, this antibody allows for the detection and analysis of C7 in a variety of cell types.C7 is known for its involvement in immune function and has been linked to various diseases, including cancer and autoimmune disorders.
By targeting C7, researchers can investigate its role in immune regulation and potentially develop new therapies for these conditions. The C7 Polyclonal Antibody offers a reliable and accurate method for studying this important protein, making it an essential tool for immunology and cancer research projects.
Product Name:
C7 Rabbit Polyclonal Antibody
SKU:
CAB5394
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 22-270 of human C7 (NP_000578.2).
This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency.
Purification Method:
Affinity purification
Gene ID:
730
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using C7 antibody (CAB5394) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
