The C6 Polyclonal Antibody (CAB10170) is a valuable tool for researchers studying C6, a cell surface molecule known for its role in immune regulation and inhibiting immune responses. Raised in rabbits, this antibody is highly reactive with human samples and validated for Western blot applications. By binding to the C6 protein, it allows for detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.C6, also referred to as an immune inhibitory receptor, is crucial for maintaining immune homeostasis by regulating inflammation and suppressing allergic reactions.
Its involvement in immune response modulation positions it as a promising target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Insight into the function of C6 is essential for the development of therapies that can harness or alter immune function in these disease contexts.
Product Name:
C6 Rabbit Polyclonal Antibody
SKU:
CAB10170
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 586-934 of human C6 (NP_000056.2).
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.
Purification Method:
Affinity purification
Gene ID:
729
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using C6 Rabbit pAb (CAB10170) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
