The C5AR2 Polyclonal Antibody (CAB10588) offered by Assaygenie is a powerful tool for researchers studying the C5AR2 protein, also known as C5a anaphylatoxin chemotactic receptor 2. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it a reliable choice for experiments involving Western blot applications.C5AR2 is a key player in the immune response, specifically in the recruitment and activation of immune cells in response to infection or injury. By targeting C5AR2 with this polyclonal antibody, researchers can accurately detect and analyze the protein in various cell types, aiding investigations in immunology and inflammation-related research.
The role of C5AR2 in immune regulation and inflammatory processes implicates its involvement in a wide range of diseases, including autoimmune disorders, inflammatory conditions, and infectious diseases. By studying the function of C5AR2 using this antibody, researchers can gain valuable insights into potential therapeutic targets for managing these conditions.In conclusion, the C5AR2 Polyclonal Antibody (CAB10588) is a valuable tool for researchers aiming to deepen their understanding of immune responses and inflammatory pathways. Its specificity and high reactivity make it a reliable choice for studies in immunology, inflammation, and related fields.
Product Name:
C5AR2 Rabbit Polyclonal Antibody
SKU:
CAB10588
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 258-337 of human C5AR2 (NP_060955.1).
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
27202
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using C5AR2 Rabbit pAb (CAB10588) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
