The Complement C3a Monoclonal Antibody is a valuable tool for researchers studying the complement system, specifically the C3a protein that plays a key role in inflammation and immune response. This antibody, produced using hybridoma technology, is highly specific to human samples and is validated for use in various applications, such as ELISA and immunohistochemistry.Complement C3a is a bioactive fragment of the complement protein C3 that contributes to the activation of immune cells and the regulation of inflammatory processes.
By targeting C3a, researchers can gain insights into the mechanisms underlying immune-mediated diseases, such as sepsis, autoimmune disorders, and inflammatory conditions.With its high specificity and reliability, the Complement C3a Monoclonal Antibody is an essential tool for researchers looking to further understand the role of the complement system in health and disease. Its versatility and effectiveness in detecting C3a make it a valuable asset for studies in immunology, inflammation, and therapeutic development.
Product Name:
Complement C3 Rabbit Monoclonal Antibody
SKU:
CAB11196
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1200-1300 of human Complement Complement C3 (P01024).
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Purification Method:
Affinity purification
Gene ID:
718
Clone Number:
ARC0541
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of HepG2 cells, using Complement Complement C3 Rabbit mAb (CAB11196) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
