The C1R Polyclonal Antibody (CAB6360) is a high-quality antibody designed for research involving the C1R protein, a key player in the complement system. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it a valuable tool for immunology and inflammation research.The C1R protein is involved in the initiation of the classical complement pathway, which plays a critical role in the immune response to pathogens and in the clearance of damaged cells. Dysregulation of the complement system has been implicated in various diseases, including autoimmune disorders and inflammatory conditions.
The C1R Polyclonal Antibody enables the detection and analysis of the C1R protein in various cell types, providing researchers with insight into its function and potential therapeutic applications.This antibody is validated for use in Western blot applications, allowing for the specific and sensitive detection of the C1R protein in experimental samples. By studying the activity of C1R, researchers can gain a better understanding of its role in immune modulation and inflammation, ultimately leading to the development of targeted therapies for diseases associated with complement dysregulation.
Product Name:
C1R Rabbit Polyclonal Antibody
SKU:
CAB6360
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 466-705 of human C1R (NP_001724.3).
This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome.
Purification Method:
Affinity purification
Gene ID:
715
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using C1R antibody (CAB6360). Blue: DAPI for nuclear staining.
