The C1QL2 Polyclonal Antibody (PAC02281) is a crucial tool for researchers studying the C1QL2 protein, a member of the C1q/TNF-related protein superfamily involved in various biological processes. This polyclonal antibody, generated in rabbits, shows high reactivity towards human samples and has been validated for Western blot applications. By specifically binding to the C1QL2 protein, researchers can accurately detect and analyze its presence in different cell types, making it an essential tool for studies in immunology, neuroscience, and developmental biology.
C1QL2 is known for its role in synaptic connectivity and plasticity in the brain, making it a key player in neurological disorders such as Alzheimer's disease and schizophrenia. Its involvement in these conditions highlights the importance of further research into its function and potential therapeutic implications. The C1QL2 Polyclonal Antibody provides researchers with a reliable means to investigate the role of C1QL2 in these complex processes and pave the way for new advancements in the field of neuroscience.
Antibody Name:
C1QL2 Antibody (PACO22281)
Antibody SKU:
PACO22281
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human C1QL2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HUVEC cells and HeLa cells, using C1QL2 antibody.
Background:
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses By similarity.
Synonyms:
Complement C1q-like protein 2;
UniProt Protein Function:
C1QL2: May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 2q14.2Cellular Component: collagen; extracellular regionMolecular Function: identical protein bindingBiological Process: protein oligomerization
